Pearly penile papules are not a subject of treatment since it is not a disease. It is not a good idea to try some ointments on your own. The best results are obtained by removing them with a CO2 laser. It is an original treatment developed by Dr. Kołtowski and it is the method preferred and practiced all over the world. Other methods, such as coagulation, aggressive ointment and freezing are painful, ineffective and leave scars.